68 research outputs found
Toward a process theory of entrepreneurship: revisiting opportunity identification and entrepreneurial actions
This dissertation studies the early development of new ventures and small business and the entrepreneurship process from initial ideas to viable ventures. I unpack the micro-foundations of entrepreneurial actions and new venturesβ investor communications through quality signals to finance their growth path. This dissertation includes two qualitative papers and one quantitative study. The qualitative papers employ an inductive multiple-case approach and include seven medical equipment manufacturers (new ventures) in a nascent market context (the mobile health industry) across six U.S. states and a secondary data analysis to understand the emergence of opportunities and the early development of new ventures. The quantitative research chapter includes 770 IPOs in the manufacturing industries in the U.S. and investigates the legitimation strategies of young ventures to gain resources from targeted resource-holders.Open Acces
Fundamental Vortices, Wall-Crossing, and Particle-Vortex Duality
We explore 1d vortex dynamics of 3d supersymmetric Yang-Mills theories, as
inferred from factorization of exact partition functions. Under Seiberg-like
dualities, the 3d partition function must remain invariant, yet it is not a
priori clear what should happen to the vortex dynamics. We observe that the 1d
quivers for the vortices remain the same, and the net effect of the 3d duality
map manifests as 1d Wall-Crossing phenomenon; Although the vortex number can
shift along such duality maps, the ranks of the 1d quiver theory are
unaffected, leading to a notion of fundamental vortices as basic building
blocks for topological sectors. For Aharony-type duality, in particular, where
one must supply extra chiral fields to couple with monopole operators on the
dual side, 1d wall-crossings of an infinite number of vortex quiver theories
are neatly and collectively encoded by 3d determinant of such extra chiral
fields. As such, 1d wall-crossing of the vortex theory encodes the
particle-vortex duality embedded in the 3d Seiberg-like duality. For , the D-brane picture is used to motivate this 3d/1d connection, while,
for , this 3d/1d connection is used to fine-tune otherwise
ambiguous vortex dynamics. We also prove some identities of 3d supersymmetric
partition functions for the Aharony duality using this vortex wall-crossing
interpretation.Comment: 75 pages, 24 figures; v2: a reference added, published versio
Plastidial Starch Phosphorylase in Sweet Potato Roots Is Proteolytically Modified by Protein-Protein Interaction with the 20S Proteasome
Post-translational regulation plays an important role in cellular metabolism. Earlier studies showed that the activity of plastidial starch phosphorylase (Pho1) may be regulated by proteolytic modification. During the purification of Pho1 from sweet potato roots, we observed an unknown high molecular weight complex (HX) showing Pho1 activity. The two-dimensional gel electrophoresis, mass spectrometry, and reverse immunoprecipitation analyses showed that HX is composed of Pho1 and the 20S proteasome. Incubating sweet potato roots at 45Β°C triggers a stepwise degradation of Pho1; however, the degradation process can be partially inhibited by specific proteasome inhibitor MG132. The proteolytically modified Pho1 displays a lower binding affinity toward glucose 1-phosphate and a reduced starch-synthesizing activity. This study suggests that the 20S proteasome interacts with Pho1 and is involved in the regulation of the catalytic activity of Pho1 in sweet potato roots under heat stress conditions
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